Your questions, answered"We know the vaccines are not 100 percent effective. Are there numbers or percentages of vaccinated people who have gotten the virus anyway? Do we know if in those cases the impact is significantly less than those without a vaccine?" —Diane in North Carolina Yes, out of the more than 100 million people who have been fully vaccinated against the coronavirus in the United States, a small number have still contracted covid-19. But the data shows that most of them were fine — and many did not even experience symptoms. Citing the most recent numbers, some 9,200 people have experienced breakthrough cases, defined as infections that occur at least 14 days after patients are fully vaccinated, and 2,525 (27 percent) of those 9,200 were asymptomatic, according to the Centers for Disease Control and Prevention. Only 835 (9 percent) were hospitalized. And a fraction — 132 (1 percent) — died. Health experts have said these numbers are not unexpected or cause for concern. “There’s nothing there yet that’s a red flag,” Anthony S. Fauci, the nation's top infectious-disease expert, said about the breakthrough cases last month at a White House news briefing. The number of hospitalizations and deaths due to breakthrough infections is small, and even so, the CDC said that 15 percent of the fatalities were reported as asymptomatic cases or unrelated to covid-19. In several cases, Fauci said the patients who died were elderly. He explained with elderly patients, particularly those with underlying health issues, they may not mount a strong immune response to the vaccine. Fauci said experts are going to closely monitor the situation, “but I don’t see anything that changes our concept of the vaccine and its efficacy.” The fact is, no vaccine is a sure thing. But in U.S. clinical trials, the Pfizer and Moderna vaccines, which use mRNA technology, were 95 percent effective at preventing covid-19. The Johnson & Johnson shot was 72 percent effective at preventing moderate illness and 85 percent effective at protecting against severe cases. In the real world, the findings seem to be fairly similar with 90 percent protection among those who took both doses of the mRNA vaccines. It has been a bumpy ride, but we are getting there. |
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